Molecular biology and functional genomics Sigma-Aldrich CompoZr, MISSION, etc.

Materials for Molecular Biology Sigma-Aldrich resources allow scientists to explore the molecular mechanisms and pathways that control all biological systems. From gene editing, DNA and RNA, oligonucleotides, and PCR to protein expression, detection, and quantitative analysis, this is an extensive supply of world–class reagents.

Types of goods: materials for cloning and expression – restriction enzymes and DNA modifying enzymes, cell-free expression systems and expression vectors using CMV promoters and FLAG tag technology, vectors, protein expression systems, reagents and resources for the transformation of bacteria and yeast, calcium phosphate-based transfection reagents, lipids and polymers for delivery DNA, etc.

materials for epiginetics and microbiome – materials for histone modification, materials for DNA methylation, chromatin immunoprecipitation kits (CHIP), RNA-binding protein immunoprecipitation kits (RIP), microbial media, microbiome standards, antibodies for microbiome research, enzymes without DNA for microbiome research, kits for microbiome DNA purification, etc.

materials for gene editing and functional genomics, genetic screening tools – proteins, single RNA clones, lentiviral packaging mixtures, control plasmid DNA, luciferase control plasmid DNA, sh-RNA libraries for genome coverage, Sanger complete genome CRISPR array libraries, combined shRNA libraries, microRNA libraries, human CRISPRi Dolcetto libraries, combined screenings for lentiviruses , etc .

kits for the preparation of the NGS library, materials for electrophoresis and hybridization of nucleic acids, materials for the purification of nucleic acids – kits for genomic DNA extraction, kits for the amplification of the entire genome, kits for the preparation of a small RNA library, kits for cleaning the library, equipment and systems for gel electrophoresis of nucleic acids, kits for DNA purification, filter PCR purification tablets, sequencing reaction purification tablets, RNA purification kits, etc.

materials for PCR and amplification – kits for genome-wide amplification, strategies for amplification of the whole genome of a single cell, materials for complete transcriptome amplification, kits for DNA and RNA amplification, PCR thermocyclers and mini-cyclers for DNA amplification, PCR plates, strips and films, pipette tips for PCR and tips with a filter, direct PCR, hot-start PCR, individual oligonucleotides and probes, DNase, kits, master mixes, primers, etc.